Ace2^{tm1(ACE2/TMPRSS2)Yjl}
Targeted Allele Detail

Summary

• Symbol: Ace2^{tm1(ACE2/TMPRSS2)Yjl}
• Name: angiotensin converting enzyme 2; targeted mutation 1, Young Lee
• MGI ID: MGI:7377565
• Synonyms: Ace2^{tm1(ACE2/TMPRSS2)Yjl}
• Gene: Ace2 Location: ChrX:162922338-162971414 bp, + strand Genetic Position: ChrX, 76.12 cM, cytoband F5
• Alliance: Ace2^{tm1(ACE2/TMPRSS2)Yjl} page
• IMPC: Ace2 gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:237616
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Ace2^{tm1(ACE2/TMPRSS2)Yjl} expresses 2 genes
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ACE2 (59272)

  Ace2	(MGI:1917258)

  human

  TMPRSS2 (7113)

  Tmprss2

  (MGI:1354381)

• The targeting construct inserted the human sequences. (J:237616)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ace2 Mutation: 73 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 1 reference(s)