Phb2^em2Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Phb2^em2Gpt
• Name: prohibitin 2; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
• MGI ID: MGI:7377022
• Synonyms: Phb2^em1Cflox, Phb2^flox
• Gene: Phb2 Location: Chr6:124689299-124693913 bp, + strand Genetic Position: Chr6, 59.17 cM
• Alliance: Phb2^em2Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 4. (J:360868)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Phb2 Mutation: 20 strains or lines available

References

• Original: J:360868 Zuo H, et al., Prohibitin 2 deficiency in photoreceptors leads to progressive retinal degeneration and facilitated Muller glia engulfing microglia debris. Exp Eye Res. 2024 May 17;244:109935
• All: 2 reference(s)