Ahr^em1Stck
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ahr^em1Stck
• Name: aryl-hydrocarbon receptor; endonuclease-mediated mutation 1, Brigitta Stockinger
• MGI ID: MGI:7367570
• Synonyms: Ahr-TdTomato
• Gene: Ahr Location: Chr12:35547978-35584988 bp, - strand Genetic Position: Chr12, 15.78 cM
• Alliance: Ahr^em1Stck page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:330307
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• Mutation details: CRISPR-targeting inserted a tdTomato reporter gene at the C terminal adding a GSG linker - P2A sequence just before the stop codon of Exon 11 (GRCm38/mm10 chr12: 35550690). (J:330307)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ahr Mutation: 109 strains or lines available

Notes

ES cell = B6N6.0 (C57BL/6N)

References

• Original: J:330307 Diny NL, et al., The aryl hydrocarbon receptor contributes to tissue adaptation of intestinal eosinophils in mice. J Exp Med. 2022 Apr 4;219(4):e20210970
• All: 4 reference(s)