Scarb2^em1Lizha
Endonuclease-mediated Allele Detail

Summary

• Symbol: Scarb2^em1Lizha
• Name: scavenger receptor class B, member 2; endonuclease-mediated mutation 1, Linguo Zhang
• MGI ID: MGI:7366922
• Gene: Scarb2 Location: Chr5:92589170-92653516 bp, - strand Genetic Position: Chr5, 46.82 cM, cytoband E3
• Alliance: Scarb2^em1Lizha page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 14 bp deletion in exon 1 resulting in a frame shift mutation. (J:330183)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scarb2 Mutation: 65 strains or lines available

References

• Original: J:330183 Zou Y, et al., The Deficiency of SCARB2/LIMP-2 Impairs Metabolism via Disrupted mTORC1-Dependent Mitochondrial OXPHOS. Int J Mol Sci. 2022 Aug 3;23(15)
• All: 1 reference(s)