Ackr3^tm2Rodb
Targeted Allele Detail

Summary

• Symbol: Ackr3^tm2Rodb
• Name: atypical chemokine receptor 3; targeted mutation 2, Robert D Berahovich
• MGI ID: MGI:7354908
• Synonyms: Cxcr7^flox
• Gene: Ackr3 Location: Chr1:90131702-90143446 bp, + strand Genetic Position: Chr1, 45.28 cM
• Alliance: Ackr3^tm2Rodb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:219310
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• A floxed allele was generated. Molecular details were not provided. (J:219310)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ackr3 Mutation: 34 strains or lines available

References

• Original: J:219310 Li X, et al., Activation of CXCR7 limits atherosclerosis and improves hyperlipidemia by increasing cholesterol uptake in adipose tissue. Circulation. 2014 Mar 18;129(11):1244-53
• All: 3 reference(s)