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Rgs2em1Jgro
Endonuclease-mediated Allele Detail
Summary
Symbol: Rgs2em1Jgro
Name: regulator of G-protein signaling 2; endonuclease-mediated mutation 1, Justin Grobe
MGI ID: MGI:7346183
Synonyms: Rgs2flox
Gene: Rgs2  Location: Chr1:143875076-143879887 bp, - strand  Genetic Position: Chr1, 62.56 cM
Alliance: Rgs2em1Jgro page
Mutation
origin
Strain of Origin:  (C57BL/6J x SJL/J)F1/J
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready)
Mutation:    Insertion
 
Mutation detailsCRISPR/cas9 genome editing uses guide RNAs (ATGAGCTTTACAAGCAGGAT and GCTGGGATGAGAGGCGCACA) toinsert loxP sited in the introns flanking exons 2-4. Rgs2 transcript Rgs2-202 was used as reference for the exon number and the guide sequences. (J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rgs2 Mutation:  21 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory