Chmp4btm2.1Alsh
Targeted Allele Detail
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Symbol: |
Chmp4btm2.1Alsh |
Name: |
charged multivesicular body protein 4B; targeted mutation 2.1, Alan Shiels |
MGI ID: |
MGI:7346082 |
Synonyms: |
Chmp4bfx |
Gene: |
Chmp4b Location: Chr2:154498949-154536703 bp, + strand Genetic Position: Chr2, 76.79 cM, cytoband H2
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Alliance: |
Chmp4btm2.1Alsh page
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Germline Transmission: |
Earliest citation of germline transmission:
J:282278
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Parent Cell Line: |
SCC10 (ES Cell)
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Strain of Origin: |
129X1/SvJ
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: The targeting vector inserted a loxP site upstream of exon 2 and a floxed neomycin resistance cassette downstream of exon 4. Cre-mediated recombination removed the selection cassette inserted downstream of exon 4.
(J:282278)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Chmp4b Mutation: |
39 strains or lines available
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Original: |
J:282278 Zhou Y, et al., A charged multivesicular body protein (CHMP4B) is required for lens growth and differentiation. Differentiation. 2019 Sep - Oct;109:16-27 |
All: |
2 reference(s) |
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