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Mettm2(MET*)Tcre
Targeted Allele Detail
Summary
Symbol: Mettm2(MET*)Tcre
Name: met proto-oncogene; targeted mutation 2, Tiziana Crepaldi
MGI ID: MGI:7345548
Synonyms: Ex14Del-ki
Gene: Met  Location: Chr6:17463799-17573979 bp, + strand  Genetic Position: Chr6, 7.83 cM, cytoband A2
Alliance: Mettm2(MET*)Tcre page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82809
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence)
Mutation:    Insertion
 
Mettm2(MET*)Tcre expresses 1 gene
 
Mutation detailsEx14Del-ki mice harbour the "humanized" knock-in mutation of the human MET allele without exon 14 that replaces the mouse Met gene. The coding region of exon 3 plus partial intron 3 was replaced with the mutant human MET CDS without exon 14" (NM_000245.4; 4032 bp). C57BL/6N ES cells were used for gene targeting. (J:82809)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Met Mutation:  82 strains or lines available
References
Original:  J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory