Tg(Vav1-MYC)10Sco
Transgene Detail

Summary

• Symbol: Tg(Vav1-MYC)10Sco
• Name: transgene insertion 10, Suzanne Cory
• MGI ID: MGI:7344345
• Synonyms: MYC10
• Transgene: Tg(Vav1-MYC)10Sco Location: unknown
• Alliance: Tg(Vav1-MYC)10Sco page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Vav1-MYC)10Sco expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MYC (4609)

  Myc	(MGI:97250)

• Mutation details: A human MYC cDNA, encompassing the coding region butlacking any 5' or 3' untranslated sequence is expressed under the control of a mouse cloned into the Vav enhancer/promoter. Three lines were generated from this construct. (J:270952)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:270952 Smith DP, et al., T-cell lymphomas mask slower developing B-lymphoid and myeloid tumours in transgenic mice with broad haemopoietic expression of MYC. Oncogene. 2005 May 19;24(22):3544-53
• All: 5 reference(s)