Tg(Pomc-luc)#Jdr
Transgene Detail

Summary

• Symbol: Tg(Pomc-luc)#Jdr
• Name: transgene insertion, Jacques Drouin
• MGI ID: MGI:7344062
• Transgene: Tg(Pomc-luc)#Jdr Location: unknown
• Alliance: Tg(Pomc-luc)#Jdr page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The pituitary-specific Pomc enhancer-containing sequence 7 kb upstream, including pituitary-specific Pomc enhancer/promoter-containing sequence 480 bp upstream of the transcription start site and the -34 to +63 bp minimal promoter, is used to drive expression of the luciferase reporter gene. Expression of the transgene is preferentially directed to anterior lobe (AL) pituitary corticotropes. (J:329224)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:329224 Langlais D, et al., A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells. Mol Endocrinol. 2011 Feb;25(2):348-59
• All: 1 reference(s)