Slc3a1^em2Mhwn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc3a1^em2Mhwn
• Name: solute carrier family 3, member 1; endonuclease-mediated mutation 2, Matthew H Wilson
• MGI ID: MGI:7343857
• Gene: Slc3a1 Location: Chr17:85335804-85371664 bp, + strand Genetic Position: Chr17, 55.17 cM
• Alliance: Slc3a1^em2Mhwn page

Mutation origin

• Strain of Origin: C57BL/6NHsd

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• CRISPR-targeting of exon 2 introduced the mutation c.526insTT (p.Glu177LeuX14). (J:301626)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc3a1 Mutation: 34 strains or lines available

References

• Original: J:301626 Beckermann TM, et al., CRISPR/Cas9 engineering of albino cystinuria Type A mice. Genesis. 2020 May;58(5):e23357
• All: 1 reference(s)