Egfr^em1Rjc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Egfr^em1Rjc
• Name: epidermal growth factor receptor; endonuclease-mediated mutation 1, Robert J Coffey
• MGI ID: MGI:7343755
• Synonyms: Egfr^Em, Egfr(tm1(EmeraldV5)Rjc
• Gene: Egfr Location: Chr11:16702203-16868158 bp, + strand Genetic Position: Chr11, 9.41 cM, cytoband A1-A4
• Alliance: Egfr^em1Rjc page

Mutation origin

• Strain of Origin: 129 x C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag, Reporter)
• Mutation: Insertion
• Mutation details: CRISPR-targeting fused an emerald reporter gene and V5 tag coding sequence before the stop codon exon 28. (J:256252)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Egfr Mutation: 89 strains or lines available

References

• Original: J:256252 Yang YP, et al., A Chimeric Egfr Protein Reporter Mouse Reveals Egfr Localization and Trafficking In Vivo. Cell Rep. 2017 May 9;19(6):1257-1267
• All: 4 reference(s)