Spp1^em1Ddov
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spp1^em1Ddov
• Name: secreted phosphoprotein 1; endonuclease-mediated mutation 1, Danyvid Olivares-Villagomez
• MGI ID: MGI:7343672
• Synonyms: Spp1^Flox
• Gene: Spp1 Location: Chr5:104582984-104588916 bp, + strand Genetic Position: Chr5, 50.68 cM
• Alliance: Spp1^em1Ddov page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exons 2 and 3. (J:287111)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Spp1 Mutation: 45 strains or lines available

References

• Original: J:287111 Nazmi A, et al., Osteopontin and iCD8alpha Cells Promote Intestinal Intraepithelial Lymphocyte Homeostasis. J Immunol. 2020 Apr 1;204(7):1968-1981
• All: 1 reference(s)