Larp6^tm1.1Yyu
Targeted Allele Detail

Summary

• Symbol: Larp6^tm1.1Yyu
• Name: La ribonucleoprotein 6, translational regulator; targeted mutation 1.1, Ying Yu
• MGI ID: MGI:7341546
• Synonyms: LARP6^flox
• Gene: Larp6 Location: Chr9:60620404-60646084 bp, + strand Genetic Position: Chr9, 32.87 cM
• Alliance: Larp6^tm1.1Yyu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:328890
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 2 was flanked by loxP sites. An FRT-flanked neomycin cassette that was inserted was removed via flp-mediated recombination. (J:328890)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Larp6 Mutation: 20 strains or lines available

References

• Original: J:328890 Zuo S, et al., ER-anchored CRTH2 antagonizes collagen biosynthesis and organ fibrosis via binding LARP6. EMBO J. 2021 Jul 5;:e107403
• All: 1 reference(s)