Atf6^em1Gwzh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Atf6^em1Gwzh
• Name: activating transcription factor 6; endonuclease-mediated mutation 1, Guo-wei Zhang
• MGI ID: MGI:7341377
• Gene: Atf6 Location: Chr1:170532243-170695340 bp, - strand Genetic Position: Chr1, 76.96 cM
• Alliance: Atf6^em1Gwzh page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology targeted exons 2 to 4 for deletion. (J:328914)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atf6 Mutation: 48 strains or lines available

References

• Original: J:328914 Zhou L, et al., ATF6 regulates the development of chronic pancreatitis by inducing p53-mediated apoptosis. Cell Death Dis. 2019 Sep 10;10(9):662
• All: 2 reference(s)