Six1^em1Kwk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Six1^em1Kwk
• Name: sine oculis-related homeobox 1; endonuclease-mediated mutation 1, Kiyoshi Kawakami
• MGI ID: MGI:7338934
• Synonyms: Six1^{em2(EGFPdelta25)}
• Gene: Six1 Location: Chr12:73088601-73093486 bp, - strand Genetic Position: Chr12, 30.34 cM
• Alliance: Six1^em1Kwk page

Mutation origin

• Strain of Origin: B6;129X1-Six1^tm2Kwk Six4^tm1Kwk/Kwk

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• TALEN-targeting deleted 25 bp from the EGFP reporter gene. (J:288236)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Six1 Mutation: 19 strains or lines available

References

• Original: J:288236 Takahashi M, et al., Six1 is required for signaling center formation and labial-lingual asymmetry in developing lower incisors. Dev Dyn. 2020 Apr 3
• All: 1 reference(s)