P2ry14^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: P2ry14^em1Cya
• Name: purinergic receptor P2Y, G-protein coupled, 14; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7336705
• Synonyms: P2Y14^-
• Gene: P2ry14 Location: Chr3:59022044-59060913 bp, - strand Genetic Position: Chr3, 28.96 cM
• Alliance: P2ry14^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/cas9 technology targeted exon 2 for deletion. (J:287143)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any P2ry14 Mutation: 34 strains or lines available

References

• Original: J:287143 Ma J, et al., Glycogen metabolism regulates macrophage-mediated acute inflammatory responses. Nat Commun. 2020 Apr 14;11(1):1769
• All: 1 reference(s)