Pdxp^tm1Xen
Targeted Allele Detail

Summary

• Symbol: Pdxp^tm1Xen
• Name: pyridoxal (pyridoxine, vitamin B6) phosphatase; targeted mutation 1, Taconic Biosciences
• MGI ID: MGI:7336686
• Synonyms: PLPP/CIN^-
• Gene: Pdxp Location: Chr15:78798119-78803717 bp, + strand Genetic Position: Chr15, 37.7 cM
• Alliance: Pdxp^tm1Xen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:272299
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• A lacZ/Neo selection cassette replaced exon 1 and part of exon 2 that includes the stop codon. (J:272299)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdxp Mutation: 4 strains or lines available

References

• Original: J:272299 Kim JE, et al., PLPP/CIN regulates bidirectional synaptic plasticity via GluN2A interaction with postsynaptic proteins. Sci Rep. 2016 May 23;6:26576
• All: 5 reference(s)