Slc38a4^em1Yzhg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc38a4^em1Yzhg
• Name: solute carrier family 38, member 4; endonuclease-mediated mutation 1, Yi Zhang
• MGI ID: MGI:7336232
• Gene: Slc38a4 Location: Chr15:96892701-96953837 bp, - strand Genetic Position: Chr15, 52.77 cM
• Alliance: Slc38a4^em1Yzhg page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intergenic deletion
• Mutation details: CRISPR/cas9 mediated recombination using guide RNAs targeting exon 3 created a deletion that removed all of exon 3. (J:328340)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc38a4 Mutation: 118 strains or lines available

References

• Original: J:328340 Xie Z, et al., Loss of Slc38a4 imprinting is a major cause of mouse placenta hyperplasia in somatic cell nuclear transferred embryos at late gestation. Cell Rep. 2022 Feb 22;38(8):110407
• All: 1 reference(s)