Fmo2^em1Tmin
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fmo2^em1Tmin
• Name: flavin containing monooxygenase 2; endonuclease-mediated mutation 1, Tohru Minamino
• MGI ID: MGI:7335251
• Gene: Fmo2 Location: Chr1:162701886-162726295 bp, - strand Genetic Position: Chr1, 70.34 cM, cytoband H1
• Alliance: Fmo2^em1Tmin page

Mutation origin

• Strain of Origin: C57BL/6NCrSlc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology targeting exon 3 generated a knockout allele. (J:328119)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fmo2 Mutation: 32 strains or lines available

References

• Original: J:328119 Yoshida Y, et al., Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism. Sci Rep. 2022 Sep 1;12(1):14883
• All: 1 reference(s)