Pebp4^em1Xyzh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pebp4^em1Xyzh
• Name: phosphatidylethanolamine binding protein 4; endonuclease-mediated mutation 1, Xiao-yan Zhou
• MGI ID: MGI:7333100
• Synonyms: PEBP4^flox
• Gene: Pebp4 Location: Chr14:70077869-70297367 bp, + strand Genetic Position: Chr14, 36.1 cM, cytoband D1
• Alliance: Pebp4^em1Xyzh page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 3. (J:327252)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pebp4 Mutation: 15 strains or lines available

References

• Original: J:327252 Qu XQ, et al., Hepatocyte-Conditional Knockout of Phosphatidylethanolamine Binding Protein 4 Aggravated LPS/D-GalN-Induced Acute Liver Injury via the TLR4/NF-kappaB Pathway. Front Immunol. 2022;13:901566
• All: 3 reference(s)