Oxtr^em1Yinn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Oxtr^em1Yinn
• Name: oxytocin receptor; endonuclease-mediated mutation 1, Yukiko U Inoue
• MGI ID: MGI:7333088
• Synonyms: Oxtr^1xPA-tdTom
• Gene: Oxtr Location: Chr6:112450644-112466904 bp, - strand Genetic Position: Chr6, 52.27 cM, cytoband E3
• Alliance: Oxtr^em1Yinn page

Mutation origin

• Strain of Origin: (C57BL/6 x C3H)F1

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag, Reporter)
• Mutation: Insertion
• Mutation details: Using CRISPR/cas9 technology, a 1xPA-tag and a T2A-tdTomato expression cassette were inserted into the Oxtr gene just upstream of the stop codon. (J:324880)

Expression

In Mice Carrying this Mutation:

74 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Oxtr Mutation: 40 strains or lines available

References

• Original: J:324880 Inoue YU, et al., Targeting Neurons with Functional Oxytocin Receptors: A Novel Set of Simple Knock-In Mouse Lines for Oxytocin Receptor Visualization and Manipulation. eNeuro. 2022 Jan-Feb;9(1):ENEURO.0423-21.2022
• All: 1 reference(s)