Kiz^tm1.1Qin
Targeted Allele Detail

Summary

• Symbol: Kiz^tm1.1Qin
• Name: kizuna centrosomal protein; targeted mutation 1.1, Qinmiao Sun
• MGI ID: MGI:7332951
• Synonyms: Gm114^-
• Gene: Kiz Location: Chr2:146697784-146812017 bp, + strand Genetic Position: Chr2, 72.63 cM
• Alliance: Kiz^tm1.1Qin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:323858
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP was inserted before exon 2 and Frt flanked Neo cassette followed by a loxP site were inserted after exon 3 in the mouse Kiz gene by targeting. The exons 2 and 3 and neo cassette were deleted by cre-mediated recombination in germ cells. (J:323858)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kiz Mutation: 39 strains or lines available

References

• Original: J:323858 Sun J, et al., KIZ/GM114 Balances the NF-kB Signaling by Antagonizing the Association of TRAF2/6 With Their Upstream Adaptors. Front Cell Dev Biol. 2022;10:877039
• All: 1 reference(s)