Klhdc8b^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Klhdc8b^em1(IMPC)J
• Name: kelch domain containing 8B; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:7330360
• Gene: Klhdc8b Location: Chr9:108324835-108338780 bp, - strand Genetic Position: Chr9, 59.37 cM, cytoband F2
• Alliance: Klhdc8b^em1(IMPC)J page
• IMPC: Klhdc8b gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences GTAACTTGATCAATTTAGAG and TTAGGTGGACTTGAGACCCC that targeted exon(s) ENSMUSE00000221531.7 ENSMUSE00001339168.2 ENSMUSE00000221526.4 ENSMUSE00000221528.4 ENSMUSE00000221530.4 ENSMUSE00000243289.4 ENSMUSE00001337153.2 ENSMUSE00001337693.2 ENSMUSE00001337938.2 ENSMUSE00001344821.2. This resulted in deletion(s) of 222 bp (location: Chr9:108324736-108324957; GRCm39), 3895 bp (location: Chr9:108324962-108328856; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Klhdc8b Mutation: 28 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)