Slc16a7^tm1.1Dgoz
Targeted Allele Detail

Summary

• Symbol: Slc16a7^tm1.1Dgoz
• Name: solute carrier family 16 (monocarboxylic acid transporters), member 7; targeted mutation 1.1, David Gozal
• MGI ID: MGI:7330170
• Synonyms: MCT2^fl, MCT2^loxP
• Gene: Slc16a7 Location: Chr10:125055139-125225334 bp, - strand Genetic Position: Chr10, 72.31 cM, cytoband D3
• Alliance: Slc16a7^tm1.1Dgoz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:315034
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A floxed allele was generated by inserting a loxP site upstream of the region to be deleted and a second loxP site, FRT site, neomycin selection cassette, third loxP site and second FRT site downstream of this region. The neomycin selection cassette was removed via flp-mediated recombination. (J:315034)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc16a7 Mutation: 29 strains or lines available

References

• Original: J:315034 Khalyfa A, et al., Monocarboxylate Transporter-2 Expression Restricts Tumor Growth in a Murine Model of Lung Cancer: A Multi-Omic Analysis. Int J Mol Sci. 2021 Sep 30;22(19)
• All: 2 reference(s)