Il2rg^tm1Vst
Targeted Allele Detail

Summary

• Symbol: Il2rg^tm1Vst
• Name: interleukin 2 receptor, gamma chain; targeted mutation 1, Beijing Vitalstar Biotechnology
• MGI ID: MGI:7329739
• Gene: Il2rg Location: ChrX:100307991-100311861 bp, - strand Genetic Position: ChrX, 43.9 cM
• Alliance: Il2rg^tm1Vst page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:327217
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (C57BL/6 x 129)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• The targeting construct deleted exons 3 through 8. (J:327217)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il2rg Mutation: 132 strains or lines available

References

• Original: J:327217 Zheng B, et al., PD-1 axis expression in musculoskeletal tumors and antitumor effect of nivolumab in osteosarcoma model of humanized mouse. J Hematol Oncol. 2018;11(1)
• All: 1 reference(s)