Gt(ROSA)26Sor^em1(Ilf3)Mxz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^em1(Ilf3)Mxz
• Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Ming-xiang Zhang
• MGI ID: MGI:7328897
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^em1(Ilf3)Mxz page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• CRISPR-targeting inserted into the locus a floxed stop cassette and the sequence for transcript 201. (J:322774)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:322774 Xie F, et al., ILF3 is responsible for hyperlipidemia-induced arteriosclerotic calcification by mediating BMP2 and STAT1 transcription. J Mol Cell Cardiol. 2021 Jul 31;161:39-52
• All: 2 reference(s)