Kl^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Kl^em1Cya
• Name: klotho; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7328435
• Synonyms: Kl^em1cyagen, Kl^fl
• Gene: Kl Location: Chr5:150876072-150917282 bp, + strand Genetic Position: Chr5, 89.77 cM, cytoband G3
• Alliance: Kl^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/cas9 created a floxed allele. (J:327076)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kl Mutation: 51 strains or lines available

References

• Original: J:327076 Du C, et al., Renal Klotho and inorganic phosphate are extrinsic factors that antagonistically regulate hematopoietic stem cell maintenance. Cell Rep. 2022 Feb 15;38(7):110392
• All: 1 reference(s)