Stox1^tm1Rkl
Targeted Allele Detail

Summary

• Symbol: Stox1^tm1Rkl
• Name: storkhead box 1; targeted mutation 1, Raghu Kalluri
• MGI ID: MGI:7328383
• Gene: Stox1 Location: Chr10:62494822-62561907 bp, - strand Genetic Position: Chr10, 32.45 cM
• Alliance: Stox1^tm1Rkl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:308988
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin cassette replaced approximately 1 kb of exon 3. (J:308988)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stox1 Mutation: 35 strains or lines available

References

• Original: J:308988 Parchem JG, et al., STOX1 deficiency is associated with renin-mediated gestational hypertension and placental defects. JCI Insight. 2021 Jan 25;6(2)
• All: 1 reference(s)