Tex11^em1Jil
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tex11^em1Jil
• Name: testis expressed gene 11; endonuclease-mediated mutation 1, endonuclease-mediated mutation 1, Jinsong Li
• MGI ID: MGI:7328366
• Synonyms: Tex11^PM
• Gene: Tex11 Location: ChrX:99882254-100103245 bp, - strand Genetic Position: ChrX, 43.72 cM
• Alliance: Tex11^em1Jil page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• Mutation details: CRISPR-targeting of exon 16 introduced 6 bp change encoding a stop codon at position 431. The truncated protein lacked the final 948 amino acids. (J:324145)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tex11 Mutation: 19 strains or lines available

References

• Original: J:324145 Wang YH, et al., Rescue of male infertility through correcting a genetic mutation causing meiotic arrest in spermatogonial stem cells. Asian J Androl. 2021 Nov-Dec;23(6):590-599
• All: 1 reference(s)