Appbp2^em1Kajim
Endonuclease-mediated Allele Detail

Summary

• Symbol: Appbp2^em1Kajim
• Name: amyloid beta precursor protein binding protein 2; endonuclease-mediated mutation 1, Shingo Kajimura
• MGI ID: MGI:7327645
• Gene: Appbp2 Location: Chr11:85082134-85125946 bp, - strand Genetic Position: Chr11, 51.34 cM, cytoband B5
• Alliance: Appbp2^em1Kajim page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/cas9 methodologies were used to flank exon 2 with loxP sites. (J:333058)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Appbp2 Mutation: 31 strains or lines available

References

• Original: J:333058 Wang Q, et al., Post-translational control of beige fat biogenesis by PRDM16 stabilization. Nature. 2022 Sep;609(7925):151-158
• All: 1 reference(s)