Prmt6^em1Caox
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prmt6^em1Caox
• Name: protein arginine N-methyltransferase 6; endonuclease-mediated mutation 1, Xuetao Cao
• MGI ID: MGI:7327536
• Gene: Prmt6 Location: Chr3:110153425-110158314 bp, - strand Genetic Position: Chr3, 48.52 cM
• Alliance: Prmt6^em1Caox page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted the coding sequence. (J:324871)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prmt6 Mutation: 22 strains or lines available

References

• Original: J:324871 Zhang H, et al., The methyltransferase PRMT6 attenuates antiviral innate immunity by blocking TBK1-IRF3 signaling. Cell Mol Immunol. 2019 Oct;16(10):800-809
• All: 1 reference(s)