Gt(ROSA)26Sor^tm1Itl
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm1Itl
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ingenious Targeting Laboratory
• MGI ID: MGI:7327503
• Synonyms: FLAG-GFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326744
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Epitope tag, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted a loxP site, FRT-flanked stop cassette, tetracycline-dependent promoter, loxP site, and FLAG-tagged EGFP reporter gene. (J:326744)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:326744 Gleixner AM, et al., NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility. Nat Commun. 2022 Jun 13;13(1):3380
• All: 1 reference(s)