Tg(Igh-LMP1)3Ratr
Transgene Detail

Summary

• Symbol: Tg(Igh-LMP1)3Ratr
• Name: transgene insertion 3, Nancy Raab-Traub
• MGI ID: MGI:7327421
• Transgene: Tg(Igh-LMP1)3Ratr Location: unknown Genetic Position: Chr12, Syntenic
• Alliance: Tg(Igh-LMP1)3Ratr page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Igh-LMP1)3Ratr involves 1 genes/genome features (Igh-J) View all
• Mutation details: Latent membrane protein 1 (LMP1) of the EpsteinBarr virus is expressed under the control of the mouse IgH enhancer and a V H promoter from a mouse hybridoma. Lines 3, 6 and 9 were generated, with line 3 studied further. In lineage 3, the transgene has integrated into the mouse Igh-J locus. (J:50151)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:50151 Kulwichit W, et al., Expression of the Epstein-Barr virus latent membrane protein 1 induces B cell lymphoma in transgenic mice. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11963-8
• All: 7 reference(s)