Nr1h4^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nr1h4^em1Cya
• Name: nuclear receptor subfamily 1, group H, member 4; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7327295
• Gene: Nr1h4 Location: Chr10:89290096-89369447 bp, - strand Genetic Position: Chr10, 44.98 cM
• Alliance: Nr1h4^em1Cya page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting deleted exons 3 and 4. (J:326788)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nr1h4 Mutation: 42 strains or lines available

References

• Original: J:326788 Lin C, et al., Obeticholic acid inhibits hepatic fatty acid uptake independent of FXR in mouse. Biomed Pharmacother. 2022 Jun;150:112984
• All: 1 reference(s)