Otud4^em1Nju
Endonuclease-mediated Allele Detail

Summary

• Symbol: Otud4^em1Nju
• Name: OTU domain containing 4; endonuclease-mediated mutation 1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:7327127
• Synonyms: Otud4^fl
• Gene: Otud4 Location: Chr8:80366305-80404384 bp, + strand Genetic Position: Chr8, 37.74 cM, cytoband C3
• Alliance: Otud4^em1Nju page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 4. (J:286922)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Otud4 Mutation: 52 strains or lines available

References

• Original: J:286922 Liuyu T, et al., Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS. Cell Res. 2019 Jan;29(1):67-79
• All: 2 reference(s)