Plxnb2^em1.1Xhl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Plxnb2^em1.1Xhl
• Name: plexin B2; endonuclease-mediated mutation 1.1, Xiang-Hang Luo
• MGI ID: MGI:7325477
• Synonyms: Plxnb2^flox
• Gene: Plxnb2 Location: Chr15:89039752-89064960 bp, - strand Genetic Position: Chr15, 44.68 cM, cytoband E3
• Alliance: Plxnb2^em1.1Xhl page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exons 8 through 10. (J:325196)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plxnb2 Mutation: 91 strains or lines available

References

• Original: J:325196 Li CJ, et al., Senescent immune cells release grancalcin to promote skeletal aging. Cell Metab. 2021 Oct 5;33(10):1957-1973.e6
• All: 1 reference(s)