Nnmt^em1Swak
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nnmt^em1Swak
• Name: nicotinamide N-methyltransferase; endonuclease-mediated mutation 1, Shu Wakino
• MGI ID: MGI:7325468
• Gene: Nnmt Location: Chr9:48503177-48516453 bp, - strand Genetic Position: Chr9, 26.45 cM
• Alliance: Nnmt^em1Swak page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Zinc Finger Nuclease technology targeted exon 2 and generated a 10 bp deletion resulting in a frameshift mutation. (J:326718)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nnmt Mutation: 21 strains or lines available

References

• Original: J:326718 Takahashi R, et al., The significance of NAD + metabolites and nicotinamide N-methyltransferase in chronic kidney disease. Sci Rep. 2022 Apr 16;12(1):6398
• All: 1 reference(s)