Tg(ACTB-lacZ,-Fgf10,-EGFP)#Mlgn
Transgene Detail

Summary

• Symbol: Tg(ACTB-lacZ,-Fgf10,-EGFP)#Mlgn
• Name: transgene insertion, Malcolm P Logan
• MGI ID: MGI:7316911
• Synonyms: Z/EGFgf10
• Transgene: Tg(ACTB-lacZ,-Fgf10,-EGFP)#Mlgn Location: unknown
• Alliance: Tg(ACTB-lacZ,-Fgf10,-EGFP)#Mlgn page

Transgene origin

• Strain of Origin: C57BL/6JNimr

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(ACTB-lacZ,-Fgf10,-EGFP)#Mlgn expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Fgf10 (MGI:1099809)

• Mutation details: The transgene contains a chicken beta actin (ACTB) promoter driving ubiquitous expression of a floxed lacZ neomycin reporter cassette with a triple stop, Fgf10 cDNA, IRES, and EGFP reporter gene. Cre-mediated recombination is required to remove the beta-geo cassette and achieve expression of Fgf10 and EGFP. (J:311931)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:311931 Duboc V, et al., Tbx4 function during hindlimb development reveals a mechanism that explains the origins of proximal limb defects. Development. 2021 Oct 1;148(19):dev199580
• All: 1 reference(s)