Kcnma1^em1Zhax
Endonuclease-mediated Allele Detail

Summary

• Symbol: Kcnma1^em1Zhax
• Name: potassium large conductance calcium-activated channel, subfamily M, alpha member 1; endonuclease-mediated mutation 1, Xuemei Zhang
• MGI ID: MGI:7316690
• Gene: Kcnma1 Location: Chr14:23342356-24055173 bp, - strand Genetic Position: Chr14, 12.92 cM
• Alliance: Kcnma1^em1Zhax page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 mediated recombination created a 532 bp deletion spanning from 23591392 to 23591923 bp including all of exon 4. (J:285431)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnma1 Mutation: 105 strains or lines available

References

• Original: J:285431 Wang Y, et al., BK ablation attenuates osteoblast bone formation via integrin pathway. Cell Death Dis. 2019 Sep 30;10(10):738
• All: 2 reference(s)