Rock2^tm1Mtbk
Targeted Allele Detail

Summary

• Symbol: Rock2^tm1Mtbk
• Name: Rho-associated coiled-coil containing protein kinase 2; targeted mutation 1, Keiichiro Matoba
• MGI ID: MGI:7316574
• Synonyms: ROCK2^flox
• Gene: Rock2 Location: Chr12:16944896-17037824 bp, + strand Genetic Position: Chr12, 8.04 cM, cytoband A3
• Alliance: Rock2^tm1Mtbk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:325405
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting mutation floxed exon 3. (J:325405)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rock2 Mutation: 62 strains or lines available

References

• Original: J:325405 Matoba K, et al., ROCK2-induced metabolic rewiring in diabetic podocytopathy. Commun Biol. 2022 Apr 8;5(1):341
• All: 1 reference(s)