Ifi27^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ifi27^em1Cya
• Name: interferon, alpha-inducible protein 27; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7316570
• Gene: Ifi27 Location: Chr12:103400470-103406498 bp, + strand Genetic Position: Chr12, 52.93 cM
• Alliance: Ifi27^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 3 through 7. (J:325412)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ifi27 Mutation: 14 strains or lines available

References

• Original: J:325412 Fan K, et al., Immune response gene 1 deficiency impairs Nrf2 activation and aggravates liver fibrosis in mice. Biochem Biophys Res Commun. 2022 Jun 4;607:103-109
• All: 1 reference(s)