Erc1^tm1.1Aakh
Targeted Allele Detail

Summary

• Symbol: Erc1^tm1.1Aakh
• Name: ELKS/RAB6-interacting/CAST family member 1; targeted mutation 1.1, Anna Akhmanova
• MGI ID: MGI:7316481
• Synonyms: GFP-Elks1
• Gene: Erc1 Location: Chr6:119547757-119825128 bp, - strand Genetic Position: Chr6, 56.86 cM, cytoband F1
• Alliance: Erc1^tm1.1Aakh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:325465
• Parent Cell Line: IB10/E14IB10 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct introduced at the start codon exon 3 a GFP reporter gene with an N-terminal peptide that can be biolinylated by biotin ligase birA and a floxed neomycin resistance cassette. Cre-mediated recombination removed the selection cassette. (J:325465)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Erc1 Mutation: 60 strains or lines available

References

• Original: J:325465 Noordstra I, et al., Organization and dynamics of the cortical complexes controlling insulin secretion in beta-cells. J Cell Sci. 2022 Feb 1;135(3):jcs259430
• All: 1 reference(s)