Mrgprb2^em1Hyal
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mrgprb2^em1Hyal
• Name: MAS-related GPR, member B2; endonuclease-mediated mutation 1, Hydar Ali
• MGI ID: MGI:7316440
• Gene: Mrgprb2 Location: Chr7:48200713-48207834 bp, - strand Genetic Position: Chr7, 31.11 cM
• Alliance: Mrgprb2^em1Hyal page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology targeted exon 2 to generate a knock-out allele. (J:326608)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mrgprb2 Mutation: 34 strains or lines available

References

• Original: J:326608 Alkanfari I, et al., Small-Molecule Host-Defense Peptide Mimetic Antibacterial and Antifungal Agents Activate Human and Mouse Mast Cells via Mas-Related GPCRs. Cells. 2019 Apr 3;8(4):311
• All: 4 reference(s)