Tgfbr1^m1Ingm
Chemically induced Allele Detail

Summary

• Symbol: Tgfbr1^m1Ingm
• Name: transforming growth factor, beta receptor I; mutation 1, Ingenium Pharmaceuticals
• MGI ID: MGI:7314840
• Synonyms: p.Y378*
• Gene: Tgfbr1 Location: Chr4:47353258-47414926 bp, + strand Genetic Position: Chr4, 26.02 cM
• Alliance: Tgfbr1^m1Ingm page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Nucleotide substitutions
• Mutation details: ENU mutagenesis created a nonsense mutation in exon 7 introducing a stop codon at position 378 (p.Y378*) (J:100122, J:262794)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tgfbr1 Mutation: 32 strains or lines available

References

• Original: J:262794 Renard M, et al., Absence of cardiovascular manifestations in a haploinsufficient Tgfbr1 mouse model. PLoS One. 2014;9(2):e89749
• All: 2 reference(s)