Procr^tm1.1Yaz
Targeted Allele Detail

Summary

• Symbol: Procr^tm1.1Yaz
• Name: protein C receptor, endothelial; targeted mutation 1.1, Yi Arial Zeng
• MGI ID: MGI:7314839
• Synonyms: Procr^flox
• Gene: Procr Location: Chr2:155593037-155597391 bp, + strand Genetic Position: Chr2, 77.26 cM, cytoband H1-3
• Alliance: Procr^tm1.1Yaz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:325492
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct floxed exons 2 through 4. Recombination removed he neomycin resistance cassette. (J:325492)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Procr Mutation: 17 strains or lines available

References

• Original: J:325492 Liu C, et al., Procr functions as a signaling receptor and is essential for the maintenance and self-renewal of mammary stem cells. Cell Rep. 2022 Mar 22;38(12):110548
• All: 1 reference(s)