Rab34^tm1Blnw
Targeted Allele Detail

Summary

• Symbol: Rab34^tm1Blnw
• Name: RAB34, member RAS oncogene family; targeted mutation 1, Baolin Wang
• MGI ID: MGI:7314833
• Gene: Rab34 Location: Chr11:78079256-78083019 bp, + strand Genetic Position: Chr11, 46.74 cM
• Alliance: Rab34^tm1Blnw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:267206
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A genomic region spanning exons 2-6 was replaced with a floxed neo cassette via homologous recombination. (J:267206)

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rab34 Mutation: 18 strains or lines available

References

• Original: J:267206 Xu S, et al., Rab34 small GTPase is required for Hedgehog signaling and an early step of ciliary vesicle formation in mouse. J Cell Sci. 2018 Nov 8;131(21):jcs213710
• All: 1 reference(s)