Ntn4^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ntn4^em1Smoc
• Name: netrin 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7314695
• Gene: Ntn4 Location: Chr10:93476911-93581834 bp, + strand Genetic Position: Chr10, 48.59 cM, cytoband C3
• Alliance: Ntn4^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 2. (J:325970)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ntn4 Mutation: 61 strains or lines available

References

• Original: J:325970 Yang H, et al., The risk variant rs11836367 contributes to breast cancer onset and metastasis by attenuating Wnt signaling via regulating NTN4 expression. Sci Adv. 2022 Jun 10;8(23):eabn3509
• All: 1 reference(s)