Htr1d^em1Zfa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Htr1d^em1Zfa
• Name: 5-hydroxytryptamine (serotonin) receptor 1D; endonuclease-mediated mutation 1, Zusen Fan
• MGI ID: MGI:7314679
• Gene: Htr1d Location: Chr4:136150835-136171709 bp, + strand Genetic Position: Chr4, 68.74 cM
• Alliance: Htr1d^em1Zfa page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 3 deleted 1 bp. (J:325980)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Htr1d Mutation: 29 strains or lines available

References

• Original: J:325980 Zhu P, et al., 5-hydroxytryptamine produced by enteric serotonergic neurons initiates colorectal cancer stem cell self-renewal and tumorigenesis. Neuron. 2022 May 7
• All: 1 reference(s)