Slc6a4^em1Zfa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc6a4^em1Zfa
• Name: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; endonuclease-mediated mutation 1, Zusen Fan
• MGI ID: MGI:7314676
• Gene: Slc6a4 Location: Chr11:76889429-76923166 bp, + strand Genetic Position: Chr11, 46.18 cM
• Alliance: Slc6a4^em1Zfa page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 2 deleted 7 bp. (J:325980)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc6a4 Mutation: 58 strains or lines available

References

• Original: J:325980 Zhu P, et al., 5-hydroxytryptamine produced by enteric serotonergic neurons initiates colorectal cancer stem cell self-renewal and tumorigenesis. Neuron. 2022 May 7
• All: 1 reference(s)